rs1006973 - FRMD6, FRMD6-AS2

Magnitude 2.0 · 1 study on file

Reported associations

• A Genome-Wide Association Study of the Protein C Anticoagulant Pathway - Unknown journal (n.d.) · Unknown authors · PubMed 22216198

  ABSTRACT: The Protein C anticoagulant pathway regulates blood coagulation by preventing the inadequate formation of thrombi. It has two main plasma components: protein C and protein S. Individuals with protein C or protein S deficiency present a dramatically increased incidence of thromboembolic disorders. Here, we present the results of a genome-wide association study (GWAS) for protein C and protein S plasma levels in a set of extended pedigrees from the Genetic Analysis of Idiopathic Thrombophilia (GAIT) Project. A total number of 397 individuals from 21 families were typed for 307,984 SNPs using the Infinium® 317 k Beadchip (Illumina). Protein C and protein S (free, functional and total) plasma levels were determined with biochemical assays for all participants. Association with pheno

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