rs10037610 - LINC01377 - LINC01019

Magnitude 2.2 · 1 study on file

Reported associations

• Investigating Genetic Determinants of Plasma Inositol Status in Adult Humans - Unknown journal (n.d.) · Unknown authors · PubMed 36774100

  ABSTRACT: ABSTRACT Background Myo-inositol (MI) is incorporated into numerous biomolecules, including phosphoinositides and inositol phosphates. Disturbance of inositol availability or metabolism is associated with various disorders, including neurological conditions and cancers, whereas supplemental MI has therapeutic potential in conditions such as depression, polycystic ovary syndrome, and congenital anomalies. Inositol status can be influenced by diet, synthesis, transport, utilization, and catabolism. Objectives We aimed to investigate potential genetic regulation of circulating MI status and to evaluate correlation of MI concentration with other metabolites. Methods GC-MS was used to determine plasma MI concentration of >2000 healthy, young adults (aged 18-28 y) from the Trinity St

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