rs10029061 - TTC29
Magnitude 2.2 · 1 study on file
Reported associations
-
Genetic Associations of Chronotype in the Finnish General Population - Unknown journal (n.d.) · Unknown authors · PubMed 32579418
ABSTRACT: Individuals with a later chronotype (evening types) tend to have unhealthier behaviors and increased morbidity and mortality as compared with those with an earlier chronotype (morning types). However, the role of genetics in explaining evening types' adverse health and health behavior is unclear. Our aim was to study genetic associations of chronotype among 8433 Finns from the cross-sectional National FINRISK 2007 and 2012 studies. First, we studied associations between chronotype and 20 key clock genes with a candidate-gene approach and then performed a full genome-wide association study (GWAS) of chronotype. We also developed a genetic risk score (GRS) for chronotype based on 313 single nucleotide polymorphisms (SNPs) that have previously been associated with chronotype. Chro
Auto-generated from study metadata. AI-synthesised commentary is added when this entry is regenerated through content-service's LLM mode.
Lifestyle context
Concrete actions anchored to the cited research. We do not prescribe, we describe.
Discuss with your doctor
-
Evening chronotype predisposition and personalized sleep strategy Moderate
Genetic finding may inform discussion of optimal sleep timing alignment with current work and social obligations
Share genetic evening chronotype predisposition result with healthcare provider for personalized guidance
Lifestyle
-
Sleep schedule alignment with evening chronotype Moderate
T allele increases evening chronotype predisposition via altered brain circadian gene expression in cerebellar regions
Assess and consider adjusting sleep times toward later schedules if your circumstances permit