rs10004839 - LINC02510
Magnitude 2.2 · 1 study on file
Reported associations
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Genome-Wide Association Study of Retinopathy in Individuals without Diabetes - Unknown journal (n.d.) · Unknown authors · PubMed 23393555
ABSTRACT: Background Mild retinopathy (microaneurysms or dot-blot hemorrhages) is observed in persons without diabetes or hypertension and may reflect microvascular disease in other organs. We conducted a genome-wide association study (GWAS) of mild retinopathy in persons without diabetes. Methods A working group agreed on phenotype harmonization, covariate selection and analytic plans for within-cohort GWAS. An inverse-variance weighted fixed effects meta-analysis was performed with GWAS results from six cohorts of 19,411 Caucasians. The primary analysis included individuals without diabetes and secondary analyses were stratified by hypertension status. We also singled out the results from single nucleotide polymorphisms (SNPs) previously shown to be associated with diabetes and hypertens
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Lifestyle context
Concrete actions anchored to the cited research. We do not prescribe, we describe.
Screening
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Retinopathy screening via comprehensive eye examination Moderate
rs10004839 in LINC02510 is associated with increased retinopathy risk in non-diabetic individuals
Annual comprehensive eye examination with dilated retinal evaluation