SGPP1, variants, traits, and what the research shows

SGPP1 is a human gene with 68 catalogued variants, including a high-magnitude signal at rs537173728, with trait associations currently under research.

High-magnitude variants on file
68
With published research summary
17
Trait themes
1

SGPP1 -- what this gene does

SGPP1 has 68 variants catalogued in this database. No trait association summaries are yet available for any of its variants, so the trait themes linked to this gene cannot be characterized from the current data alone.

Key takeaways

  • SGPP1 has 68 catalogued variants, with one reaching a notably high magnitude score.
  • The highest-magnitude variant on record is rs537173728, at a magnitude score of 4.50.
  • A cluster of additional variants each carry a magnitude score of 3.00, suggesting a broad variant landscape worth watching as research summaries arrive.
  • Magnitude scores reflect the estimated size of an association signal and do not indicate direction, trait, or clinical relevance without supporting trait data.
  • Trait association data for this gene is not yet available in this database.

Notable variants

The highest-magnitude variant catalogued for this gene is rs537173728, at a magnitude score of 4.50. A broad cluster of variants also on file each score at magnitude 3.00, including rs1023547121, rs1265379919, rs139614441, rs1432111212, rs1483138817, rs1595076271, and rs1884967771, among others. No trait metadata is attached to any of these variants in the current data set.

Trait associations

No trait associations are available for this gene in the current data set. As research summaries are processed for the 17 variants flagged with prior literature, this section will be expanded with specific traits, effect sizes, and study references.

Evidence quality

This gene has 68 variants on file, with 17 flagged as having prior research literature, but no trait summaries have been loaded into this database yet. Without effect sizes, odds ratios, sample sizes, or replication data in the current input, the evidence base cannot be assessed beyond noting that the variant catalogue is relatively broad and that the highest-magnitude signal, rs537173728 at 4.50, stands meaningfully above the 3.00 cluster.

What this is NOT

These variants are population-level statistical signals, not deterministic predictors for any individual. This database does not prescribe, diagnose, or advise.


Traits this gene affects

Top variants in SGPP1

Highest-impact rsids on file, sorted by magnitude. Linked entries have a full research summary; unlinked entries are in the catalog but not yet written up.

rsidMagnitudePrimary trait
rs5371737284.5
rs10235471213.0
rs12653799193.0
rs1396144413.0
rs14321112123.0
rs14831388173.0
rs15950762713.0
rs18849677713.0
rs18859099983.0
rs25494885153.0
rs25494979893.0
rs3677451423.0
rs3706919973.0
rs3712489743.0
rs3742473903.0
rs7462232903.0
rs7493300713.0
rs7496798623.0
rs7521768423.0
rs7593093253.0