NLRP3, variants, traits, and what the research shows

Plain-English summary of the NLRP3 gene: 551 high-magnitude variants on file, 11 with published research summaries. Variants linked to immune, hearing, rare_disease.

High-magnitude variants on file
551
With published research summary
11
Trait themes
3

Traits this gene affects

  • immune
  • hearing
  • rare_disease

Top variants in NLRP3

Highest-impact rsids on file, sorted by magnitude. Linked entries have a full research summary; unlinked entries are in the catalog but not yet written up.

rsidMagnitudePrimary trait
rs1048953985.5immune
rs10575155315.5hearing
rs11316912985.5rare_disease
rs1172873515.5hearing
rs1219081475.5hearing
rs1219081505.5hearing
rs1219081515.5hearing
rs1219081525.5immune
rs1219081535.5hearing
rs1219081545.5immune
rs12481564755.5hearing
rs13427904565.5rare_disease
rs13519934485.5hearing
rs1389468945.5hearing
rs1398338745.5hearing
rs1398523705.5hearing
rs1413897115.5hearing
rs1435489795.5hearing
rs1452680735.5hearing
rs1457744005.5rare_disease