HMGB1, variants, traits, and what the research shows
Plain-English summary of the HMGB1 gene: 39 high-magnitude variants on file, 8 with published research summaries. Variants linked to rare_disease, cardiovascular.
- High-magnitude variants on file
- 39
- With published research summary
- 8
- Trait themes
- 2
Traits this gene affects
- rare_disease
- cardiovascular
Top variants in HMGB1
Highest-impact rsids on file, sorted by magnitude. Linked entries have a full research summary; unlinked entries are in the catalog but not yet written up.
| rsid | Magnitude | Primary trait |
|---|---|---|
| rs2500460578 | 5.5 | rare_disease |
| rs2500460631 | 5.5 | rare_disease |
| rs2137396956 | 5.0 | rare_disease |
| rs2500473984 | 5.0 | rare_disease |
| rs181753401 | 4.5 | cardiovascular |
| rs185989172 | 4.5 | rare_disease |
| rs1026945082 | 3.0 | rare_disease |
| rs1051864412 | 3.0 | rare_disease |
| rs1555232131 | 3.0 | rare_disease |
| rs190839668 | 3.0 | rare_disease |
| rs2137392488 | 3.0 | |
| rs1045411 | 2.2 | metabolic |
| rs10541209 | 2.2 | |
| rs111608625 | 2.2 | metabolic |
| rs112612237 | 2.2 | |
| rs11618202 | 2.2 | |
| rs116471547 | 2.2 | |
| rs11842871 | 2.2 | metabolic |
| rs12431309 | 2.2 | |
| rs144392104 | 2.2 |