EYA2, variants, traits, and what the research shows

EYA2 - what this gene does

EYA2 has 128 variants catalogued in the current dataset, with the available trait data pointing toward neurological associations. The two highest-magnitude signals are carried by rs4809613 and rs878131.

Key takeaways

• EYA2 has 128 variants on file, with trait data pointing toward neurological associations.
• rs4809613 is the highest-magnitude variant (4.50) and carries an explicit neurological trait link.
• rs878131 ties for the top magnitude score (4.50) but has no trait detail currently on file.
• Most remaining variants carry a magnitude of 3.00 with no trait metadata available yet.
• Full SNP-level research summaries for this gene are not yet published; this entry reflects the variant list only.

Notable variants

rs4809613 and rs878131 are the two highest-ranked variants in the dataset, each carrying a magnitude score of 4.50. Of these, only rs4809613 has a trait label on file, specifically a neurological trait. A broader set of variants - including rs1211922780, rs1298648031, rs1351585017, rs138717634, and rs141317409 - each carry a magnitude score of 3.00, but no specific trait annotations are recorded for them at this time.

Trait associations

The only trait theme in the current dataset is neurological. Among all 128 on-file variants, rs4809613 is the sole variant carrying an explicit neurological trait annotation. No other specific conditions or phenotypes are attached to the remaining variants in the dataset. Because only one variant has a trait label, replication across multiple variants within this gene cannot yet be assessed.

Evidence quality

No prior research summaries are yet available for the 17 variants flagged as having prior research in this gene. Because effect sizes, odds ratios, sample sizes, and replication status are absent from the current data, the strength and direction of any association cannot be evaluated. The single neurological trait tag on rs4809613 is the only trait-level signal present. This entry should be treated as preliminary until full SNP-level summaries are published.

What this is NOT

These variants are population-level statistical signals and are not deterministic predictors of any outcome for any individual. Nothing on this page constitutes a prescription, diagnosis, or recommendation of any kind.