DRAM1, variants, traits, and what the research shows

DRAM1 - what this gene does

Variants recorded for DRAM1 are primarily linked to neurological traits based on the data available. The leading signal is rs7964241, the highest-magnitude variant on file for this gene, which is associated with a neurological trait.

Key takeaways

• The top variant, rs7964241, is linked to a neurological trait and carries the strongest evidence score in this gene's dataset.
• Across 77 variants on file, the dominant trait theme is neurological.
• Most associations here are GWAS signals (genome-wide association studies - large scans linking DNA variants to traits across many people), reflecting population-level patterns rather than individual predictions.
• A number of variants at magnitude 3.00 and 2.20 are recorded but currently lack annotated trait detail.
• All associations should be treated as preliminary signals pending broader replication.

Notable variants

The highest-priority variant is rs7964241 (magnitude 4.50), annotated as neurological and representing the clearest signal available for this gene. A cluster of 13 variants at magnitude 3.00 - including rs1053469717, rs1234792963, and rs200817899, among others - are on file but carry no annotated trait data in the current dataset. At magnitude 2.20, six variants are recorded: rs10860822, rs11111075, rs11111084, rs11111088, rs117081218, and rs11610520. Five of these have published pages, though no summary content was available for this entry.

Trait associations

The only trait directly annotated in the current dataset is neurological, linked to rs7964241. The remaining variants - spanning the magnitude 3.00 group and the magnitude 2.20 group - do not carry annotated trait data in the available input, so no additional trait claims can be grounded here. The overall trait theme flagged for this gene is neurological.

Evidence quality

The strongest signal on file is rs7964241 at magnitude 4.50, annotated as neurological. No effect size, sample size, or cohort information is available in the current dataset for any variant. Five variants hold published pages (rs10860822, rs11111075, rs11111084, rs11111088, rs117081218), but no summary content was provided, preventing any assessment of replication status. Of the 77 total variants on file, the majority carry no annotated trait detail. Treat all signals here as preliminary findings that require independent replication before broader conclusions are drawn.

What this is NOT

These variants are population-level statistical signals, not deterministic predictors for any individual. Nothing on this page constitutes medical advice, a diagnosis, or a recommendation to take any action.