DPF3, variants, traits, and what the research shows

DPF3 - what this gene does

Variants at the DPF3 locus have appeared in GWAS research - genome-wide association studies that scan large populations for genetic variants statistically linked to traits - in connection with vision. No detailed per-variant study summaries are on file, so the sections below describe what magnitude scores and trait tags alone show.

Key takeaways

• The DPF3 locus has 94 variants on record, with four reaching the highest magnitude tier in the dataset.
• Vision is the primary trait theme associated with this gene based on available data.
• Most catalogued variants do not carry specific trait labels, limiting what can be reported with confidence.
• These associations are population-level statistical signals, not deterministic predictors for any individual.
• Effect sizes and replication statistics are not available in the current dataset.

Notable variants

The four highest-ranked variants are rs2079989, rs28667150, rs7152005, and rs933632776, each at magnitude 4.50. Of these, rs28667150 is the only one in this tier carrying an explicit trait tag, linking it to vision. A second tier - including rs1313292844, rs1318429711, rs1411834661, and rs1886660226 among others - sits at magnitude 3.00 without specific trait labels in the current data.

Trait associations

Vision is the primary documented trait theme for this locus. rs28667150 is the top-magnitude variant with an explicit vision-related tag. The broader pool of 94 catalogued variants falls within the same general trait theme, though individual trait labels beyond rs28667150 are not available in the current data. Multiple variants converging on the same trait theme at a single locus is consistent with a genuine biological connection, but replication data is not on file here to confirm that interpretation.

Evidence quality

The data on file consists of variant magnitude scores and a single confirmed trait tag for rs28667150 (vision). No GWAS summary statistics such as odds ratios, p-values, or cohort sizes are available for any individual variant in this dataset. All findings here should be treated as preliminary signals pending full study-level data and independent replication across independent cohorts.

What this is NOT

These variants are population-level statistical signals, not deterministic predictors for any individual. This page does not prescribe, diagnose, or advise any course of action.