DNASE1, variants, traits, and what the research shows
Plain-English summary of the DNASE1 gene: 87 high-magnitude variants on file, 1 with published research summaries. Variants linked to rare_disease, kidney, cancer.
- High-magnitude variants on file
- 87
- With published research summary
- 1
- Trait themes
- 6
Traits this gene affects
- rare_disease
- kidney
- cancer
- immune
- pharmacogenomics
Top variants in DNASE1
Highest-impact rsids on file, sorted by magnitude. Linked entries have a full research summary; unlinked entries are in the catalog but not yet written up.
| rsid | Magnitude | Primary trait |
|---|---|---|
| rs138615105 | 5.5 | rare_disease |
| rs1455872989 | 5.5 | rare_disease |
| rs201975812 | 5.5 | rare_disease |
| rs2548299083 | 5.5 | kidney |
| rs61756352 | 5.5 | cancer |
| rs774864487 | 5.5 | rare_disease |
| rs8176928 | 5.5 | rare_disease |
| rs77254040 | 5.0 | immune |
| rs35275535 | 4.5 | pharmacogenomics |
| rs1002016730 | 3.0 | |
| rs1049863556 | 3.0 | |
| rs111987725 | 3.0 | |
| rs1192511571 | 3.0 | |
| rs1196061726 | 3.0 | |
| rs1197651306 | 3.0 | |
| rs1325824229 | 3.0 | |
| rs1380987022 | 3.0 | |
| rs1384987863 | 3.0 | |
| rs1394621043 | 3.0 | |
| rs140622851 | 3.0 |