COMT, variants, traits, and what the research shows
Plain-English summary of the COMT gene: 33 high-magnitude variants on file, 2 with published research summaries. Variants linked to rare_disease, , cancer.
- High-magnitude variants on file
- 33
- With published research summary
- 2
- Trait themes
- 4
Traits this gene affects
- rare_disease
- cancer
- cardiovascular
Top variants in COMT
Highest-impact rsids on file, sorted by magnitude. Linked entries have a full research summary; unlinked entries are in the catalog but not yet written up.
| rsid | Magnitude | Primary trait |
|---|---|---|
| rs2517476743 | 5.5 | rare_disease |
| rs1109436 | 4.5 | |
| rs140215652 | 4.5 | |
| rs9332377 | 4.5 | cancer |
| rs9606194 | 4.5 | |
| rs1159919237 | 3.0 | cardiovascular |
| rs1173322116 | 3.0 | cardiovascular |
| rs1230683925 | 3.0 | cardiovascular |
| rs1429174414 | 3.0 | cardiovascular |
| rs145228139 | 3.0 | |
| rs1465316102 | 3.0 | cardiovascular |
| rs2517445051 | 3.0 | cardiovascular |
| rs2517445068 | 3.0 | cardiovascular |
| rs571085983 | 3.0 | cardiovascular |
| rs6267 | 3.0 | mental_health |
| rs749057584 | 3.0 | cardiovascular |
| rs761671459 | 3.0 | cardiovascular |
| rs770596060 | 3.0 | |
| rs775392322 | 3.0 | cardiovascular |
| rs866665461 | 3.0 | cardiovascular |