BANP, variants, traits, and what the research shows

BANP - what this gene does

BANP appears in genome-wide association data (GWAS - a study that scans many people's genomes for variants statistically associated with a trait) primarily in the context of cardiovascular traits. Based on the variants catalogued here, the clearest theme across the highest-magnitude signals is cardiovascular biology.

Key takeaways

• Several high-magnitude variants near BANP have been linked to cardiovascular traits in population-level genetic research.
• The strongest signals carry a magnitude score of 4.50, a relative measure combining effect size and evidence strength.
• The cardiovascular signal appears across multiple independent variants at this locus, which strengthens the pattern relative to a single isolated finding.
• 84 total variants are catalogued for this gene, with 18 carrying prior research summaries.
• These are statistical associations from large population studies, not deterministic health predictions for any individual.

Notable variants

The highest-magnitude variants on file all score 4.50. Among those with explicit cardiovascular trait labels are rs114700275, rs114908471, rs116213227, and rs138575291. rs11117317 and rs141103485 also reach the top magnitude tier, though specific trait details for those entries are not present in the current data. A second tier of variants including rs1157702891 and rs1205198992 carry a magnitude of 3.00 and are catalogued but lack detailed trait summaries at this time.

Trait associations

The dominant trait theme across the highest-confidence variants is cardiovascular. Four of the six top-magnitude (4.50) variants - specifically rs114700275, rs114908471, rs116213227, and rs138575291 - carry cardiovascular trait labels. The appearance of a consistent cardiovascular signal across multiple independent variants at the same locus is a meaningful pattern, though specific effect sizes, odds ratios, and sub-phenotypes within the cardiovascular category are not available in the current data extract.

Evidence quality

The four top-tier cardiovascular-linked variants each carry a magnitude score of 4.50, reflecting a combination of effect size and evidence weight. Detailed per-variant statistics such as exact odds ratios, beta coefficients, and sample sizes are not available in the current data for these entries, limiting the ability to characterize strength of association precisely. The broader catalogue includes 84 variants total, with 18 carrying prior research summaries, indicating this locus has attracted meaningful research attention. Until per-variant study-level data is confirmed, these associations should be treated as directional signals rather than firmly replicated findings, and any single-cohort results should be considered preliminary.

What this is NOT

These variants are population-level statistical signals, not deterministic predictors for any individual. This page does not prescribe, diagnose, or advise any course of action.